It is a condition caused due to gastric contents into the esophagus and proximal structures.
Clinical Presentation:
- symptoms- heart burn and regurgitation
- Atypical chest pain
- Extraesophageal manifestations-cough,laryngitis,asthma and dental erosions. Also there may be sinusitis,pulmonary fibrosis,pharyngitis and recurrent otitis media.
- Response to therapeutic trial of PPI can be diagnostic but a negative response does not exclude the disease
- Endoscopy to rule out other causes of such esophageal symptoms, like eosinophilic esophagitis,candidial esophagitis etc
- 24hrs esophageal pH monitoring (investigation of choice)
- Esophageal manometry to identify motos process contributing to refractory symptoms
- Antacids,histamine-2 receptor antagonists,PPI may relieve symptoms in mild and intermittent conditions
- PPI(Proton Pump inhibitors) are more effective than other treatment modalities.
- In conditions not responding to medical treatment,they are surgically managed by Nissen's Fundoplication
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