Peripheral neuropathy

These patients will complaint of numbness in hands and feet that progresses proximally in a distribution classically termed as 'glove &stocking'
Causes:

1. Idiopathic (most common)
2. Diabetes mellitus
3. Vit B12,E deficiencies
4. Carcinoma
5. Drugs eg : isoniazid,dapsone,vinca alkaloids,cisplatin, gold, metronidazole
6. Paraproteinemias eg : myeloma
7. Rare causes like amyloidosis,GBS,sarcoidosis etc

Investigation of choice:

             Nerve conduction studies